Relationship between dental infections and uveitis: considerations for healthcare professionals. A narrative literature review
DOI:
https://doi.org/10.18537/fouc.v04.n02.a09Keywords:
uveitis, inflammation, microbiota, periodontal diseases, eyesAbstract
Abstract
Introduction: odontogenic diseases are conditions that not only compromise the oral cavity but may also extend to other organs, including the eyes. Such dissemination can result in ocular inflammatory processes, most notably uveitis, facilitated by anatomical relationships and vascular connections. This pathology is emphasized due to the limited research currently available. Objective: to describe the relationship between dental infections and uveitis. Methodology: a narrative literature review was conducted, focusing on case reports and descriptive observational studies, both crosssectional and retrospective, published between 2012 and 2025 in Spanish and English. Conclusion: evidence indicates that oral infections can serve as infectious foci for ocular diseases such as uveitis. This underscores the close link between oral and ocular health, highlighting the importance of early diagnosis and timely treatment to prevent severe complications.
Downloads
References
Arjunan P, Swaminathan R. Do oral pathogens
inhabit the eye and play a role in ocular
diseases? J Clin Med. 2022;11:6694. doi:10.3390/
jcm11226694.
González-Palomino B, Naranjo-García A, FerreraSierra Y, Bárzaga-Quiroga T, Peña-Sisto M, LugoGuerrero DE. Manifestaciones oftalmológicas
de infecciones odontogénicas. Rev 16 de Abril
[Internet]. 2021, 60(282):e1272. http://www.
rev16deabril.sld.cu/index.php/16_4/article/
view/1272
Preda MA, Sarafoleanu C, Mușat G, Preda AA,
Lupoi D, Barac R, et al. Management of oculoorbital complications of odontogenic sinusitis
in adults. Rom J Ophthalmol. 2024;68(1):45-52.
doi:10.22336/rjo.2024.09
Sánchez Sánchez RJ, Feria Díaz GE, Miguel Cruz
PA. Salud bucal y enfermedades sistémicas.
Gac Méd Espirit [Internet]. 2024;26. https://
revgmespirituana.sld.cu/index.php/gme/article/
view/2612;
Sun X, Li M, Xia L, Fang Z, Yu S, Gao J, et al.
Alteration of salivary microbiome in periodontitis
with or without type-2 diabetes mellitus and
metformin treatment. Sci Rep. 2020;10(1):15363.
doi:10.1038/s41598-020-72035-1.
Dumitrache M, Manea M. Eye oculo-orbital
disease due to dental causes. Int J Family Med
Healthcare. 2024;3(4):1-5. doi:10.33425/2833-
1030
Mendiburu Zavala CEPS, Arce Cen DJ, MedinaPeralta S, Carrillo Mendiburu J. Prevalencia de
enfermedades pulpares o periapicales como
factores de riesgo de la uveítis secundaria. Rev
Odontol Mex. 2016;20(1):22-28. doi:10.1016/j.
rodmex.2016.02.003.
OpenAI. ChatGPT [Internet]. 2025. Relación entre
la cavidad oral y ocular. https://chatgpt.com/s/m_
b7e088191a4ee364a9330a129
Peña Sisto M, Peña Sisto L, Calzado de Silva
M, Rodríguez Alonso Y, Santos Toledo L. Focos
sépticos bucales en pacientes con uveítis.
Medisan. 2012;16(12):1852-1859. http://scielo.
sld.cu/pdf/san/v16n12/san061612.pdf
Li C, Yu R, Ding Y. Association between
Porphyromonas gingivalis and systemic diseases:
focus on T cells-mediated adaptive immunity.
Front Cell Infect Microbiol. 2022;12:1026457.
doi:10.3389/fcimb.2022.1026457
Arguimbau-Coll M, Serrano-Stefanova A,
Jorva-García-de Casasola C, Egido-Moreno S,
Omaña-Cepeda C, López-López J. Marcadores
inflamatorios de la periodontitis y su papel en la
inflamación sistémica: revisión sistemática. Av
Odontoestomatol. 2025;41(spe):63-87. https://
scielo.isciii.es/scielo.php?script=sci_arttext&pi
d=S0213-12852025000100007
Oh E, Jun JH, Choi JY, Yoo TK. Systemic
inflammation at the oral-ocular interface: a
P medicine perspective on the relationship
between periodontitis and eye diseases. EPMA J.
;16(3):571-587. doi:10.1007/s13167-025-00415-6.
Chau SF, Lee CY, Huang JY, Chou MC, Chen HC,
Yang SF. The existence of periodontal disease and
subsequent ocular diseases: a population-based
cohort study. Medicina (Kaunas). 2020;56(11):621.
doi:10.3390/medicina56110621.
Hoopes H, Cloutier N. A case of endogenous
endophthalmitis after a mild dental infection. J
Am Coll Emerg Physicians Open. 2021;2(5):e12557.
doi:10.1002/emp2.12557
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Revista de la Facultad de Odontología de la Universidad de Cuenca
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
