GASTROINTESTINAL MANIFESTATIONS AS A PHENOTYPIC EXPRESSION OF COVID-19: A BIBLIOGRAPHIC REVIEW

Authors

DOI:

https://doi.org/10.18537/RFCM.39.03.08

Keywords:

SARS-CoV-2, COVID-19, diarrhea

Abstract

Introduction: the appearance of the new SARS-CoV-2 and its rapid spread poses a global health emergency. This virus mainly affects the respiratory system, but also the gastrointestinal tract.

Objective: to identify if gastrointestinal manifestations secondary to Covid-19 infection are a phenotypic and important expression of this pathology.

Methodology: a systematic search was carried out in scientific medical journals in the databases: Scielo, PubMed, SpringerLink, Wile Online Library, Scopus with the following terms "Gastrointestinal Manifestations by COVID-19", "Gastrointestinal symptoms by SARS-COV2", "Gastrointestinal disorders in COVID-19", published in English and Spanish between 2020 and 2021.

Results: the most prevalent gastrointestinal symptoms were diarrhea, nausea, vomiting, anorexia and abdominal pain. The pathophysiology of gastrointestinal manifestations depends on angiotensin converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2). The detection of viral RNA in feces as a diagnosis has been detected in 53.4% ​​of infected patients, other methods described are not definitive. Finally, the treatment of gastrointestinal manifestations by COVID-19 is symptomatic.

Conclusions: The advances in epidemiology, pathogenesis, clinical characteristics, means of diagnosis and treatment of COVID-19, show that the secondary gastrointestinal manifestations present in a variable form and frequency, allowing to face the epidemic COVID-19 in a more effective way.

 

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Author Biographies

Cristina Nataly Fernández Collahuazo , University of Cuenca

Médico Residente de Segundo Grado de la Especialidad de Medicina Interna. Universidad de Cuenca. Cuenca, Ecuador.

Mayra Estefanía Idrovo Macancela , University of Cuenca

Médico Residente de Segundo Grado de la Especialidad de Medicina Interna. Universidad de Cuenca. Cuenca, Ecuador.

Janina Tatiana Torres Arévalo , University of Cuenca

Médico Residente de Segundo Grado de la Especialidad de Medicina Interna. Universidad de Cuenca. Cuenca, Ecuador.

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Published

2021-12-29

Issue

Vol. 39 No. 3 (2021): Revista de la Facultad de Ciencias Médicas de la Universidad de Cuenca

Section

Bibliographic Review

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Copyright (c) 2021 Cristina Nataly Fernández Collahuazo , Mayra Estefanía Idrovo Macancela , Janina Tatiana Torres Arévalo , Lorena Esperanza Encalada Torres

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