Granulomatosis with polyangiitis (Wegener's) with gastrointestinal bleeding. Case report

Authors

  • Jessica Anabel López Valencia . Posgradista de la Universidad de Cuenca. Especialidad Medicina Interna. Cuenca - Ecuador https://orcid.org/0000-0002-8319-559X
  • Marcia Janneth Bermeo Cabrera Hospital Municipal de Cuenca. Unidad de Medicina Interna. Medicina Interna. Cuenca - Ecuador https://orcid.org/0000-0003-0483-1592
  • Goethe Salomón Sacoto Flores Universidad de Cuenca. Facultad de Ciencias Médicas. Carrera de Medicina. Cuenca - Ecuador https://orcid.org/0000-0002-8114-0114

DOI:

https://doi.org/10.18537/RFCM.40.01.09

Keywords:

granulomatosis with polyangiitis, vasculitis, hemorrhage, pathology

Abstract

Introduction: ANCA-associated vasculitides (AAV) are characterized by inflammation of small caliber blood vessels and a high percentage of positivity for antineutrophil cytoplasmic antibodies (ANCA).

Clinical case: It is a case of a 74-year-old mestizo man, with dysphonia, weight loss, superficial erythematous lesions distributed in lower limbs. One week prior to admission, he presented rectal bleeding, diffuse abdominal pain with clinical data of hypovolemic shock, ulcerative colitis was identified (colonoscopy) and positive serology for PR3-ANCA. Immunosuppressive treatment was started with favorable evolution.

Conclusion: AAV have variable clinical phenotypes with forms from mild to fulminant, they should be suspected early, treated promptly to favorably influence their prognosis.

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Published

2022-05-21