Stevens-Johnson syndrome due to drug use: case report

Authors

  • Danilo Fernando Orellana Cobos Universidad de Cuenca. Facultad de Ciencias Médicas. Carrera de Medicina. Cuenca - Ecuador https://orcid.org/0000-0001-6269-5512
  • Paola Gabriela Delgado Andrade Hospital San Martín de Porres, Unidad de Nutrición. Cuenca-Ecuador https://orcid.org/0000-0003-1117-2054
  • Ana Belén Orellana Cobos Universidad Católica de Cuenca, Departamento de Posgrados. Cuenca-Ecuador https://orcid.org/0000-0002-8002-5181
  • Carlos Gabriel Quezada Urdiales Estudiante de la carrera de Medicina de la Universidad del Azuay. Cuenca-Ecuador https://orcid.org/0000-0003-3683-5539
  • Byron Fernando Quituisaca Vizhñay Estudiante de la carrera de Medicina de la Universidad del Azuay. Cuenca-Ecuador

DOI:

https://doi.org/10.18537/RFCM.40.03.07

Keywords:

Stevens-Johnson syndrome, simvastatine, clopidogrel

Abstract

Stevens-Johnson syndrome is a severe mucocutaneous hypersensitivity generally triggered by drugs. Clinically, it is characterized by the presence of maculopapular lesions that spread and merge quickly; causing blisters, necrosis and epidermal dichatement. The diagnosis is mainly clinical, early support therapy and strict monitoring is crucial. The following is a case of a 59 year old female, who after 5 days of ingesting zopiclone, simvastatin and clopidogrel presented violaceus erythematous maculopapular lesions on abdomen, chest and extremities. Paraclinical tests resulted negative for autoimmune diseases, an improvement of the patient’s health was observed after the use of corticosteroids and suspending the medication that were causing the disease. An early clinical diagnosis allowed an appropriate intervention and favorable evolution; thus, the importance of this case report.

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Published

2022-12-09

Issue

Vol. 40 No. 3 (2022): Revista de la Facultad de Ciencias Médicas de la Universidad de Cuenca

Section

Clinical Case

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Copyright (c) 2022 Danilo Fernando Orellana Cobos

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