Refractory Autoimmune Inflammatory Myopathy

Refractory Autoimmune Inflammatory Myopathy: case report

Authors

DOI:

https://doi.org/10.18537/RFCM.41.03.06

Keywords:

PalabraMiopatías inflamatorias idiopáticas, Dermatomiositis, Miopatía inflamatoria refractaria

Abstract

Introduction: Idiopathic inflammatory myopathies (IIM) are a group of autoimmune connective tissue diseases characterized by muscle inflammation and clinical involvement of multiple organs such as the skin, lungs, heart, and gastrointestinal tract. Clinical case: A case of IIM with muscle weakness, dysphagia and skin manifestations, refractory to treatment, is presented. The initial immunosuppressive treatment with azathyprine and glucocorticoids (GC) had a poor response. As a second line of therapy, intravenous cyclophosphamide plus GC was administered with clinical improvement and decrease in muscle enzymes. Conclusion: IIM refractory to treatment carry a poor prognosis, and other associated causes that explain this lack of response such as infections, neoplasms, or other non-autoimmune inflammatory myopathies should always be ruled out. Keywords: idiopathic inflammatory myopathies, dermatomyositis, refractory inflammatory myopathy.

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Published

2023-12-01

Issue

Vol. 41 No. 3 (2023): Revista de la Facultad de Ciencias Médicas de la Universidad de Cuenca

Section

Clinical Case

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Copyright (c) 2023 Goethe Salomón Sacoto Flores, Dra Soledad

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