Cervical cancer and pregnancy. Case report

Authors

DOI:

https://doi.org/10.18537/RFCM.43.02.09

Keywords:

uterine cervical neoplasms, pregnancy, drug therapy

Abstract

Introduction: Cervical cancer has an incidence of 1 in 1.000 pregnancies, a condition that raises uncertainties: when should chemotherapy be initiated, and how long should it be administered to minimize maternal-fetal complications? What is the best surgical treatment?

Clinical Case: A 30-year-old nulliparous patient was diagnosed at 14 weeks of pregnancy with squamous cell carcinoma of the cervix, clinical stage IIB. The patient began chemotherapy at 18 weeks, receiving 5 cycles. At 34 weeks, a cesarean section followed by a radical hysterectomy was performed. Pathology confirmed a 3 cm tumor with 2 out of 11 metastatic lymph nodes. Adjuvant treatment included chemo-radiotherapy and brachytherapy was applied. One year after surgery, both the patient and the baby are in excellent condition.

Conclusions: This case highlights the feasibility of active oncologic management during pregnancy, with chemotherapy in the second trimester and oncologic surgery after fetal viability, with favorable outcomes for both mother and fetus.

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Published

2025-08-04