Breast cancer in pregnancy. Case report

Authors

DOI:

https://doi.org/10.18537/RFCM.43.01.09

Keywords:

breast neoplasms, pregnancy in adolescence, drug therapy

Abstract

Introduction: Breast cancer is the most common neoplasia diagnosed during pregnancy. Diagnosis and treatment options must be tailored to ensure maternal and fetal well-being.

Clinical case: A 34-year-old woman with a history of HER2-positive ductal carcinoma of the right breast (2018) treated with chemotherapy, surgery, and radiotherapy, with no local recurrence. In 2023, the patient presented nodules in the contralateral chest wall and abdomen. Biopsies confirmed luminal B ductal carcinoma (second primary). The chemotherapy began in the second trimester of pregnancy. At 30 weeks, a cesarean section was performed, with satisfactory maternal and fetal well-being. Brain metastases were subsequently treated with radiotherapy. At the moment the patient is asymptomatic.

Conclusion: Multidisciplinary management allowed a balanced treatment between the oncologic treatment and pregnancy viability, achieving satisfactory maternal and neonatal outcomes. Chemotherapy administered during pregnancy was well tolerated. At one year of follow-up, the mother is in good general condition, and the child's psychomotor development is adequate.

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Published

2025-04-01