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Composite lymphoma in an 18-year-old patient with uncharacteristic initial symptoms. Case report

Authors

  • Andrés Fernando Andrade Fuentes Médico. Master Universitario en Dirección y Gestión Sanitaria. Libre ejercicio. Quito-Pichincha-Ecuador. https://orcid.org/0000-0001-6386-9713
  • Kevin Steven Miranda Suárez Médico Cirujano. Hospital de Especialidades Carlos Andrade Marín. Unidad de Urgencias Adultos. Quito-Pichincha-Ecuador. https://orcid.org/0000-0002-9357-4067
  • Miguel Jacob Ochoa Andrade Médico. Hospital General del Sur de Quito. Instituto Ecuatoriano de Seguridad Social (IESS). Equipo Técnico. Subdirección de Auditoría Médica. Quito-Pichincha-Ecuador. https://orcid.org/0000-0001-5505-5285

DOI:

https://doi.org/10.18537/RFCM.39.03.06

Keywords:

composite lymphoma, Hodgkin disease, lymphoma non-Hodgkin, lymphoma B-cell

Abstract

Introduction: Composite lymphoma is a rare condition that is composed of two or more different lymphomas in the same tissue or topographical site, its cause is unknown, its origin could be due to clonal selection, genomic instability and/or factors involved with the Epstein Barr virus.

Clinical case: a clinical case with classic Hodgkin lymphoma (HL) and diffuse B-cell lymphoma is presented, initially characterized by chronic cough, weight loss, night sweats and inguinal lymphadenopathy, which evolved with the presence of pulmonary and cervical lymphadenopathy.  Histopathological studies showed features of a little known entity resulting in the simultaneity of two types of lymphomas, characteristic of this pathology.

Conclusions: the clinical and laboratory findings of compound lymphoma are very important, they serve as a reference in medical care, in order to be able to identify this type of pathology in time and provide appropriate management.

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Published

2022-03-30

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