Control HSMC para regulación de glucosa sanguínea
Abstract
RESUMEN
Este artículo propone una nueva estrategia de control basada en medidas continuas de glucosa y un controlador por modo deslizante que se habitúa (HSMC). El HSMC es desarrollado, combinando la ley de control por modo deslizante y los principios de control por habituación. El HSMC aplicado a la regulación de glucosa sanguínea en la unidad de cuidados intensivos, incluye tanto entrada de glucosa, como de infusión de insulina intravasculares a fin de proveer el suministro de nutrición y mejorar el rechazo a la perturbación. El estudio basado en simulaciones (in silico), usando un modelo fisiológico de la dinámica glucosa-insulina, muestra que la estrategia de control propuesta funciona apropiadamente. Finalmente, se compara el desempeño del controlador propuesto con respecto a un controlador PID estándar.
Palabras clave: Control por modo deslizante, control por habituación, regulación de glucosa sanguínea.
ABSTRACT
This article proposes a new strategy of control based on continue measurements of glucose and a habituating sliding mode controller (HSMC). The HSMC is developed combining the sliding mode control law and the principles of habituating control. The HSMC applied to the regulation of blood glucose in the intensive care unit, includes both intravascular glucose and insulin infusion inputs to provide the nutrition supply and to improve the rejection to disturbances. The simulation based study (in silico), using a physiological model of the dynamic glucose-insulin, shows that proposed control strategy works properly. Finally, the performance of the proposed controller and a standard PID controller are compared.
Keywords: Sliding mode control, habituating control, blood glucose regulation.
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